Prof.Dr.Yusufhan Süoğlu
Branş Kulak, Burun ve Boğaz Hastalıkları
Telefon 0212 239 96 86 0532 411 75 25
Web Sitesi http://www.yusufhansuoglu.com
Adres Valikonağı cad.Prof.Dr.Müfide Küley sk.Çamlıbel apt.51/1,Nişantaşı- İstanbul
İl/İlçe İstanbul
Doktor Hakkında
Eğitim Bilgileri
Mezun Olduğu Okul
1995
İSTANBUL ÜNİVERSİTESİ İSTANBUL TIP FAKÜLTESİ
KULAK BURUN BOĞAZ-BAŞ&BOYUN CERRAHİSİ Istanbul(Avrupa)
Eğitim Sertifikaları
1997Clinical Fellowship: Marburg University, Fulda Teaching Hospital,ENT-Head&Neck and Facial Plastic Surgery.Fulda,Germany
2002Doç.Dr.İÜ.İstanbul Tıp Fak.KBB Hast.AD
2004Clinical Fellowship: Virginia University, ORL-H&N Department,Facial Plastic and Reconstructive Surgery. International Fellowship, USA
2004Oregon Health&Science University, ORL-H&N Department,Facial Plastic and Reconstructive Surgery. International Fellowship, USA
2007Prof.Dr.İÜ.İstanbul Tıp Fak.KBB Hast.AD
İşDeneyimi
1991 - Halen - İSTANBUL ÜNİVERSİTESİ İSTANBUL TIP FAKÜLTESİ-KBB HASTALIKLARI ANABİLİM DALI
Mesleki Üyelikleri
Türk KBB ve Baş Boyun Cerrahisi Derneği
Türk Larengoloji Derneği
Avrupa Rinoloji Derneği
Avrupa Fasyal Plasti Akademisi
Yüz Plastik Cerrahi Deneği (Kurucu Üye, Yönetim Kurulu Üyesi, Genel Sekreter)
Tıbbi Yayınlar
1- Revision surgery in cochlear implantation Orhan KS, Celik M, Başaran B, Ulusan M, Comoğlu S, Karabulut B, Süoğlu Y, Güldiken Y, Değer K. Kulak Burun Bogaz Ihtis Derg. 2012 Nov-Dec;22(6):311-8. doi: 10.5606/kbbihtisas.2012.060. Turkish. PMID: 23176694 [PubMed - in process] 2- Radiation-induced osteosarcoma of the larynx:a case report and literature review. Ulusan M, Yilmazer R, Ozluk Y, Enoz M, Suoglu Y. Ear Nose Throat J. 2012 Oct;91(10):E22-5. PMID: 23076859 [PubMed - in process] 3- The use of botulinum toxin type A in masseteric muscle hypertrophy: long-term effects and lasting improvement Aydil B, Başaran B, Unsaler S, Süoğlu Y. Kulak Burun Bogaz Ihtis Derg. 2012 Sep-Oct;22(5):249-53. doi: 10.5606/kbbihtisas.2012.049. Turkish. PMID: 22991984 [PubMed - in process] 4- Promoter methylation and loss of p16(INK4a) gene expression in head and neck cancer Demokan S, Chuang A, Suoğlu Y, Ulusan M, Yalnız Z, Califano JA, Dalay N. Head Neck. 2012 Oct;34(10):1470-5. doi: 10.1002/hed.21949. Epub 2011 Nov 22. PMID: 22106032 [PubMed - in process] 5- Yalniz, Z ; Demokan, S; Suoglu, Y ; Ulusan, M ; Dalay, N Title: Simultaneous Methylation Profiling of Tumor Suppressor Genes in Head and Neck Cancer Source: DNA AND CELL BIOLOGY, 30 (1): 17-24 JAN 2011 Abstract: Head and neck cancer (HNC) is a common cancer, and its prognosis has not changed during the last decades. Detection of the disease at an early stage is crucial for successful treatment, as early diagnosis can significantly increase the survival rate. Methylation of tumor suppressor genes is an early event in cancer responsible for incorrect gene silencing. Since methylation changes are reversible, they also provide a promising target for therapy. So far, only individual genes have been analyzed for aberrant methylation in HNC. In this study, we analyzed the methylation status of 24 tumor suppressor genes simultaneously by methylation-specific multiplex ligation-dependent probe amplification in matched tumor and normal tissue samples from patients with HNC. CHFR, RAR beta, DAPK1, and RASFF1 genes were the most frequently methylated genes in tumor tissue. Eight genes were not methylated in any sample. The methylation frequencies for individual genes ranged from 0% to 19%. Our results indicate that methylation of tumor suppressor genes is not high as previously reported by methylation-specific polymerase chain reaction and is confined to a smaller but significant fraction of the tumors. Whether this group represents a unique entity in the disease spectrum warrants further studies. ISSN: 1044-5498 DOI: 10.1089/dna.2010.1090 6- Ulusan M, Enöz M, Kumral TL, Süoğlu Y. The effect of tumor width and depth on extracapsular lymp node metastases in tongue tumors., Kulak Burun Bogaz Ihtis Derg. 2010 Jan-Feb;20(1):18-24 7- Demokan, S (Demokan, Semra); Suoglu, Y (Suoglu, Yusufhan); Gozeler, M (Gozeler, Mustafa); Demir, D (Demir, Deniz); Dalay, N (Dalay, Nejat) Title: N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer Source: MOLECULAR BIOLOGY REPORTS, 37 (7): 3217-3226 OCT 2010 Abstract: Polymorphisms that alter the function of genes involved in the activation or detoxification of carcinogenic compounds can influence an individuals risk of developing cancer. Polymorphic changes modulating the acetylation capacity of the N-acetyltransferase (NAT) genes have been implicated in the risk of developing cancer. In this study the role of genetically determined individual NAT1 and NAT2 genotypes, haplotypes and haplotype combinations in the predisposition to head and neck cancer was investigated. Polymorphic regions of the NAT1 and NAT2 genes were analyzed in patients with head and neck cancer and healthy individuals by polymerase chain reaction-restriction fragment length polymorphism. Distribution of the genotypes, allele frequencies, diplotypes and haplotypes and correlation with clinical characteristics were evaluated. No association was observed between the NAT1*3, NAT1*10, NAT1*11, NAT2*5 and NAT2*6 genotypes and risk of head and neck cancer. The NAT2*7 slow genotype was associated with reduced risk of disease. A significant association was observed between the fast acetylator NAT2*4/NAT1*10 diplotype and risk of head and neck cancer. Combined haplotypes harboring the T1088A and C1095A variants characterizing the NAT1*10 allele were associated with increased risk. Our results suggest that NAT1 and NAT2 gene combinations may influence the risk of developing head and neck cancer. ISSN: 0301-4851 DOI: 10.1007/s11033-009-9905-8 8- Yalniz, Z (Yalniz, Zubeyde); Demokan, S (Demokan, Semra); Suoglu, Y (Suoglu, Yusufhan); Ulusan, M (Ulusan, Murat); Dalay, N (Dalay, Nejat) Title: Assessment of microsatellite instability in head and neck cancer using consensus markers Source: MOLECULAR BIOLOGY REPORTS, 37 (7): 3541-3545 OCT 2010 Abstract: Head and neck cancer is the sixth most common cancer in the world and one of the most lethal cancers. Microsatellite instability is an important characteristic of tumor cells and is observed both in presence and absence of http://pcs.isiknowledge.com/uml/uml_view.cgi?
